Cobblestone ulcerations in the bowel are seen in which of the following disease
- AOption (a)
Intestinal obstruction
- BOption (b)
Crohn's disease
- COption (c)
Malabsorption syndrome
- DOption (d)
Ulcerative colitis
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Correct answer
Crohn's disease
Why this answer is correct
Concept:
- Inflammatory Bowel Disease (IBD): It represents a group of intestinal disorders that cause prolonged inflammation of the digestive tract.
- Mainly refers to two disease conditions:
- Regional enteritis ( Crohn's disease)
- Ulcerative colitis.
Explanation:
- Crohn's Disease: It is a chronic, replacing, and remitting inflammatory disease of the gastrointestinal tract affecting any site from mouth to anus.
- Commonly occur among adolescents & young adults, but can occur in any lifetime.
- It can occur anywhere along the GI tract but most commonly affects Ilium & Colon.
- Lesions or ulcers occurring in Crohn's disease are not continuous ( separated by normal tissue) known as Cobblestone appearance.
- Cobblestone ulcer result from inflammation in the intestine in Crohn's disease.
- Rectal involvement, bleeding, and diarrhoea are less
- Patients with Crohn's disease are at increased risk for colon cancer.
Additional Information
- Ulcerative Colitis: It is a disease that causes mucosal inflammation and sores (ulcers) in the lining of the large intestine ( colon).
- Peak incidence AGE IS 30-50.
- The disease process starts at the rectum and affects continuous the entire colon.
- Lesions or ulcers are continuous and occur one after another.
- Rectal involvement bleeding and diarrhoea are common.
- The risk of colon cancer is as less compared to Crohn's disease.
- Intestinal Obstruction:
- Its blockage or obstruction in the intestinal tract prevents the normal flow of content via the intestine.
- Types of obstruction:
- Mechanical obstruction: Intraluminal obstruction due to pressure on the intestinal wall, e.g. tumour, adhesion, stricture, stenosis, intussusception, etc.
- Functional obstruction: Intestinal obstruction musculature cannot propel the content through the bowel.