In which phase of cell cycle, synthesis of histone protein occurs?
- AOption (a)
G1-Phase
- BOption (b)
S-Phase
- COption (c)
G2-Phase
- DOption (d)
M-Phase
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Correct answer
S-Phase
Why this answer is correct
The correct answer is S-Phase.
Concept:
- Cell cycle is an orderly sequence of events or a set of stages by which a cell duplicates its genome, synthesis the other constituents (important for the cell) of the cell and eventually divides into two daughter cells.
- Phases of Cell Cycle
- A typical eukaryotic cell (human cell) divides once in every 24hr. This duration of cell cycle can vary from an organism to other organism and also from one cell type to another.
Explanation:
- The cell cycle is divided into two phases:
- Interphase:
- It is the period between the end of one cell division to the beginning of the next cell division, i.e., (between two successive M-phase).
- During this phase, cell prepares itself for both cell growth and DNA replication in an orderly manner. So, it is also known as preparation phase.
- Interphase is further divided into the following three substages on the basis of various synthetic activities.
- G1 (Gap -1) - phase
- It corresponds to the duration between the mitosis (M-phase) and initiation of replication of DNA.
- In this phase, cell grows continuously and prepares itself for DNA replication.
- Thus, synthesizing enzymes and proteins needed for this process.
- S (Synthesis) -phase
- It is known to be the phase in which the actual synthesis of histone protein occurs and replication of DNA takes place.
- To provide nucleosomes to the new DNA, massive amounts of new histones are required immediately at the start of the S period of DNA synthesis.
- The overall amount of DNA doubles per cell, but no increase in chromosome number takes place during this phase.
- G2 (Gap - 2) - phase
- This phase is also called post-synthetic or pre-mitotic phase.
- During this stage, the synthesis of DNA stops and proteins required for mitosis are being synthesised while, the growth of cell continues.
- M-phase:
- Following the interphase, the cell enters the M-phase or mitotic phase.