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Question 391

Combined Defence Services (CDS) 2025• English

Which instrument is used to measure the blood pressure manually?

  1. AOption (a)

    Sphygmomanometer

  2. BOption (b)

    Centrifuge

  3. COption (c)

    Electrophoresis

  4. DOption (d)

     Thermal cycler

View answer & explanation

Correct answer

Answer: (a)A.

Sphygmomanometer

Why this answer is correct

The correct answer is Sphygmomanometer.

Key Points

  • A Sphygmomanometer is a medical instrument used to measure blood pressure manually.
  • The device typically consists of an inflatable cuff, a measuring unit (manometer), and a mechanism for inflation (bulb or pump).
  • Blood pressure is measured in millimeters of mercury (mmHg) and recorded as two numbers: systolic pressure (higher) over diastolic pressure (lower).
  • Manual sphygmomanometers are commonly used with a stethoscope to listen to the arterial blood flow sounds during measurement.
  • It is widely used by healthcare professionals for accurate and reliable blood pressure readings.

Additional Information

  • Types of Sphygmomanometers
  • There are three main types: Mercury, Aneroid, and Digital sphygmomanometers.
  • Mercury sphygmomanometers are considered the gold standard for accuracy.
  • Aneroid devices use a mechanical gauge and require regular calibration.
  • Digital devices are user-friendly and suitable for home use but may have slight accuracy variations.
  • Korotkoff Sounds
  • These are the sounds heard through a stethoscope while measuring blood pressure using a manual sphygmomanometer.
  • They indicate changes in blood flow and are used to determine systolic and diastolic pressures.
  • Hypertension and Hypotension
  • Hypertension: High blood pressure, typically defined as 140/90 mmHg or higher.
  • Hypotension: Low blood pressure, typically below 90/60 mmHg.
  • Both conditions require accurate measurement for diagnosis and treatment.
  • Importance of Blood Pressure Monitoring
  • Regular monitoring helps in early detection of cardiovascular diseases.
  • It aids in managing chronic conditions like hypertension and diabetes.
  • Monitoring is crucial during pregnancy to prevent complications such as preeclampsia.

Question 392

Combined Defence Services (CDS) 2025• English

Myopia is also known as:

  1. AOption (a)

    Far-sightedness

  2. BOption (b)

    Near-sightedness

  3. COption (c)

    Cataract

  4. DOption (d)

    Presbyopia

View answer & explanation

Correct answer

Answer: (b)B.

Near-sightedness

Why this answer is correct

The correct answer is Near-sightedness.

Key Points

  • Myopia, commonly known as near-sightedness, is a refractive error where individuals can see nearby objects clearly but struggle to see distant objects.
  • It occurs when the light entering the eye focuses in front of the retina instead of directly on it.
  • Common symptoms include blurry vision of distant objects, eye strain, and headaches.
  • Myopia is often caused by elongation of the eyeball or an overly curved cornea or lens.
  • The condition can be corrected using concave lenses in glasses or contact lenses, or through refractive surgery like LASIK.

Additional Information

  • Myopia vs. Hypermetropia:
  • Myopia: Difficulty seeing distant objects, corrected with concave lenses.
  • Hypermetropia (Far-sightedness): Difficulty seeing nearby objects, corrected with convex lenses.
  • Presbyopia: A common age-related condition where the eye's lens loses flexibility, making it difficult to focus on close objects. It typically starts around age 40.
  • Astigmatism: A refractive error caused by an irregularly shaped cornea or lens, leading to blurred or distorted vision at all distances.
  • Preventive Measures: While myopia cannot always be prevented, practices such as reducing screen time, taking regular breaks while reading, and spending time outdoors can help reduce its progression.
  • Global Prevalence: Myopia is becoming increasingly common worldwide, with studies suggesting that nearly 50% of the global population may be myopic by 2050 due to lifestyle changes and increased near-work activities.

Question 393

Combined Defence Services (CDS) 2025• English

Why does the Rough Endoplasmic Reticulum look 'rough' under a microscope?

  1. AOption (a)

    Due to the presence of ribosomes on its surface

  2. BOption (b)

    Due to the absence of ribosomes on its surface

  3. COption (c)

    Due to the presence of lysosomes on its surface

  4. DOption (d)

    Due to the presence of mitochondria on its surface

View answer & explanation

Correct answer

Answer: (a)A.

Due to the presence of ribosomes on its surface

Why this answer is correct

The correct answer is Due to the presence of ribosomes on its surface.

Key Points

  • The Rough Endoplasmic Reticulum (RER) appears "rough" under a microscope because it is studded with ribosomes on its cytoplasmic surface.
  • Ribosomes are responsible for protein synthesis, which is one of the primary functions of the RER.
  • The association of ribosomes with the RER gives it a granular or rough appearance when viewed under an electron microscope.
  • The RER is particularly abundant in cells that are actively involved in protein secretion, such as pancreatic cells and plasma cells.
  • These ribosomes synthesize proteins that are either secreted from the cell, incorporated into the plasma membrane, or used within lysosomes.

Additional Information

  • Endoplasmic Reticulum (ER):
  • The ER is an extensive network of membranes found in eukaryotic cells, divided into two types: Rough ER (RER) and Smooth ER (SER).
  • The RER is involved in protein synthesis and modification, while the SER is involved in lipid synthesis and detoxification processes.
  • Ribosomes:
  • Ribosomes are small organelles composed of RNA and proteins, responsible for assembling polypeptides during protein synthesis.
  • They can be free-floating in the cytoplasm or attached to the RER.
  • Protein Secretion Pathway:
  • Proteins synthesized on the RER are transported to the Golgi apparatus for modification and packaging.
  • They are then sent to their final destinations: secretion, plasma membrane insertion, or lysosome incorporation.
  • Electron Microscopy:
  • The granular appearance of the RER was first observed using electron microscopes, which provide detailed cellular images.
  • This technique allows scientists to study the ultrastructure of organelles like the RER and ribosomes.

Question 394

Combined Defence Services (CDS) 2025• English

Which one among the following is not a plant hormone?

  1. AOption (a)

    Gibberellins

  2. BOption (b)

    Abscisic acid

  3. COption (c)

    Auxins

  4. DOption (d)

    Thyroxine

View answer & explanation

Correct answer

Answer: (d)D.

Thyroxine

Why this answer is correct

The correct answer is Thyroxine.

Key Points

  • Thyroxine is a hormone secreted by the thyroid gland and is not classified as a plant hormone.
  • It plays a vital role in regulating metabolism, heart rate, and body temperature in animals and humans.
  • Plant hormones, also known as phytohormones, include substances like gibberellins, abscisic acid, and auxins, which regulate plant growth and development.
  • Gibberellins, auxins, and abscisic acid are essential for processes such as seed germination, cell elongation, and stress responses in plants.
  • Thyroxine is specific to animals and humans, making it distinct from plant hormones.

Additional Information

  • Plant Hormones Overview:
  • Auxins: Promote cell elongation and are involved in phototropism and gravitropism.
  • Gibberellins: Stimulate seed germination, stem elongation, and fruit development.
  • Abscisic Acid: Plays a key role in stress responses such as drought tolerance by closing stomata.
  • Cytokinins: Promote cell division and delay leaf aging.
  • Ethylene: Regulates fruit ripening and response to stress.
  • Thyroxine (T4) in Humans and Animals:
  • Produced by the thyroid gland and controlled by the pituitary gland through thyroid-stimulating hormone (TSH).
  • Essential for energy metabolism, growth, and development in animals.
  • An imbalance in thyroxine levels can cause disorders such as hypothyroidism or hyperthyroidism.
  • Differences Between Plant and Animal Hormones:
  • Plant hormones regulate growth, development, and responses to environmental stimuli.
  • Animal hormones, like thyroxine, regulate metabolic and physiological processes in the body.
  • Plant hormones are often multifunctional, while animal hormones have more specialized roles.
  • Phytohormones vs. Synthetic Hormones:
  • Phytohormones are naturally occurring in plants, while synthetic hormones are artificially created for agricultural use.
  • Examples of synthetic plant hormones include 2,4-D (a synthetic auxin) used as a herbicide.

Question 395

Combined Defence Services (CDS) 2025• English

The normal systolic pressure in human beings is:

  1. AOption (a)

    80 mm of Hg

  2. BOption (b)

    100 mm of Hg

  3. COption (c)

    120 mm of Hg

  4. DOption (d)

    140 mm of Hg

View answer & explanation

Correct answer

Answer: (c)C.

120 mm of Hg

Why this answer is correct

The correct answer is 120 mm of Hg.

Key Points

  • The normal systolic blood pressure in a healthy adult human is considered to be 120 mm of Hg, as defined by global medical standards.
  • Systolic pressure refers to the maximum pressure exerted on artery walls during the contraction of the heart's left ventricle.
  • A systolic blood pressure reading of less than 120 mm of Hg is regarded as normal, according to the American Heart Association (AHA).
  • Blood pressure is typically measured in millimeters of mercury (mmHg) and is represented as a ratio of systolic to diastolic pressure, for example, 120/80 mmHg.
  • Consistently high systolic pressure (≥130 mmHg) can indicate hypertension, which increases the risk of heart disease, stroke, and other health complications.

Additional Information

  • Diastolic Pressure:
  • It is the minimum pressure in the arteries when the heart rests between beats.
  • The normal diastolic pressure is 80 mm of Hg.
  • A diastolic pressure reading of ≥90 mmHg is considered high and may indicate hypertension.
  • Hypertension (High Blood Pressure):
  • A condition where the blood pressure consistently exceeds 130/80 mmHg.
  • It is a major risk factor for cardiovascular diseases, kidney damage, and stroke.
  • Hypotension (Low Blood Pressure):
  • Occurs when blood pressure drops below 90/60 mmHg.
  • Can lead to dizziness, fainting, and in severe cases, shock.
  • Blood Pressure Measurement:
  • Blood pressure is measured using a device called a sphygmomanometer.
  • The measurement includes two numbers: systolic (upper) and diastolic (lower) pressure.
  • Factors Affecting Blood Pressure:
  • Age, stress, diet, physical activity, and underlying medical conditions can influence blood pressure levels.
  • Maintaining a healthy lifestyle, including a balanced diet and regular exercise, is crucial for blood pressure management.

Question 396

Combined Defence Services (CDS) 2025• English

Sponges belong to which one among the following phylum?

  1. AOption (a)

    Porifera

  2. BOption (b)

    Platyhelminthes

  3. COption (c)

    Cnidaria

  4. DOption (d)

    Annelida

View answer & explanation

Correct answer

Answer: (a)A.

Porifera

Why this answer is correct

The correct answer is Porifera.

Key Points

  • Sponges belong to the phylum Porifera, which is characterized by organisms having porous bodies.
  • Porifera are multicellular organisms that lack true tissues and organs, making them one of the simplest animals.
  • Sponges are sessile (fixed in place) and primarily marine organisms, although a few freshwater species exist.
  • They use specialized cells called choanocytes to filter water and extract nutrients from it.
  • Sponges reproduce both sexually and asexually, and their skeletal structure is made of either spongin fibers or spicules composed of calcium carbonate or silica.

Additional Information

  • Porifera comes from the Latin word "porus" (meaning pore) and "ferre" (meaning to bear), referring to the porous structure of these animals.
  • Sponges exhibit a type of body organization known as the cellular level of organization, where different cell types perform specific functions but do not form tissues.
  • Water enters a sponge's body through tiny pores called ostia and exits through a larger opening called the osculum.
  • Sponges are vital components of marine ecosystems, serving as filter feeders that help clean water and provide habitats for other organisms.
  • Other phyla mentioned in the options include:
  • Platyhelminthes: Flatworms, characterized by a flat body and bilateral symmetry.
  • Cnidaria: Jellyfish, corals, and sea anemones, known for their stinging cells (cnidocytes).
  • Annelida: Segmented worms like earthworms and leeches.

Question 397

Combined Defence Services (CDS) 2025• English

Lactose is made up of:

  1. AOption (a)

    Glucose only

  2. BOption (b)

    Glucose and Fructose

  3. COption (c)

    Glucose and Sucrose

  4. DOption (d)

    Glucose and Galactose

View answer & explanation

Correct answer

Answer: (d)D.

Glucose and Galactose

Why this answer is correct

The correct answer is Glucose and Galactose.

Key Points

  • Lactose is a disaccharide sugar composed of one molecule of glucose and one molecule of galactose linked by a β-1,4-glycosidic bond.
  • Lactose is commonly found in milk and dairy products and is often referred to as "milk sugar."
  • It serves as a primary source of energy for young mammals and is broken down in the digestive system by the enzyme lactase.
  • Individuals with lactose intolerance lack sufficient lactase enzyme, leading to difficulty digesting lactose.

Additional Information

  • Disaccharides:
  • These are carbohydrates composed of two monosaccharides linked by a glycosidic bond.
  • Examples include sucrose (glucose + fructose), maltose (glucose + glucose), and lactose (glucose + galactose).
  • Lactase Enzyme:
  • Lactase is produced in the small intestine and is responsible for breaking lactose into glucose and galactose.
  • A deficiency in lactase leads to lactose intolerance.
  • Lactose Intolerance:
  • A condition where individuals experience symptoms like bloating, gas, and diarrhea after consuming lactose-containing foods.
  • It is more common in adults and varies in prevalence among different populations globally.
  • Nutritional Importance:
  • Lactose enhances calcium absorption in the body, promoting bone health.
  • It is a significant energy source in infant nutrition, especially during breastfeeding.

Question 398

Combined Defence Services (CDS) 2025• English

The enzymes which catalyze the same reaction but have different amino acid compositions are commonly referred as :

  1. AOption (a)

    Isoenzymes

  2. BOption (b)

    Isotopes

  3. COption (c)

    Isomers

  4. DOption (d)

    Coenzymes

View answer & explanation

Correct answer

Answer: (a)A.

Isoenzymes

Why this answer is correct

The correct answer is Isoenzymes.

Key Points

  • Isoenzymes are enzymes that catalyze the same chemical reaction but differ in their amino acid sequences and structure.
  • They are encoded by different genes and may vary in their kinetic properties, regulatory mechanisms, or tissue-specific expression.
  • Isoenzymes often play a key role in adapting enzyme activity to specific tissues or developmental stages.
  • A classic example of isoenzymes is lactate dehydrogenase (LDH), which has multiple forms adapted for different tissues such as the heart and skeletal muscles.
  • These enzymes provide functional diversity and help in maintaining metabolic control under varying physiological conditions.

Additional Information

  • Coenzymes:
  • Coenzymes are organic molecules that bind to enzymes and assist in catalyzing reactions.
  • Examples include NAD+ (Nicotinamide Adenine Dinucleotide) and FAD (Flavin Adenine Dinucleotide).
  • They act as carriers for chemical groups or electrons during enzymatic reactions.
  • Isomers:
  • Isomers are molecules with the same molecular formula but different structural arrangements.
  • They are not related to enzymatic activity but are important in organic chemistry.
  • Isotopes:
  • Isotopes are atoms of the same element that have different numbers of neutrons, leading to varying atomic masses.
  • They are used in radiological studies and not associated with enzyme function.
  • Lactate Dehydrogenase (LDH) Isoenzymes:
  • LDH has five isoenzymes (LDH-1 to LDH-5) that are tissue-specific.
  • LDH-1 is primarily found in the heart, while LDH-5 is predominant in the liver and muscles.

Question 399

Combined Defence Services (CDS) 2025• English

How many Carbon atoms are present in a Pyruvate molecule ?

  1. AOption (a)

    2

  2. BOption (b)

    3

  3. COption (c)

    4

  4. DOption (d)

    5

View answer & explanation

Correct answer

Answer: (b)B.

3

Why this answer is correct

The correct answer is 3.

Key Points

  • A pyruvate molecule contains 3 carbon atoms, forming the basic structure of this compound.
  • It is the end product of glycolysis, a key metabolic pathway in cellular respiration.
  • During glycolysis, one molecule of glucose (6 carbon atoms) is broken down into two molecules of pyruvate, each containing 3 carbon atoms.
  • Pyruvate can undergo further metabolic processes such as conversion to acetyl-CoA or fermentation depending on oxygen availability.
  • The chemical formula of pyruvate is C3H4O3, confirming the presence of 3 carbon atoms in its structure.

Additional Information

  • Glycolysis:
  • Glycolysis is the metabolic pathway that converts glucose into pyruvate, producing ATP and NADH in the process.
  • This pathway occurs in the cytoplasm of cells and does not require oxygen, making it an anaerobic process.
  • Glycolysis consists of 10 enzymatic steps and is a fundamental part of cellular respiration.
  • Pyruvate Decarboxylation:
  • In the presence of oxygen, pyruvate is converted into acetyl-CoA in the mitochondria, a process essential for the Krebs cycle.
  • This step produces NADH and releases carbon dioxide.
  • Fermentation:
  • Under anaerobic conditions, pyruvate can undergo fermentation to produce lactate in animals or ethanol and carbon dioxide in yeast.
  • Fermentation regenerates NAD+, allowing glycolysis to continue in the absence of oxygen.
  • Importance of Pyruvate:
  • Pyruvate is a central metabolite and acts as a key junction in various metabolic pathways.
  • It connects anaerobic glycolysis to aerobic respiration and fermentation.

Question 400

Combined Defence Services (CDS) 2025• English

The human eye has a point that lacks photoreceptor cells. This is identified as :

  1. AOption (a)

    Fovea

  2. BOption (b)

    Blind spot

  3. COption (c)

    Dark spot

  4. DOption (d)

    Orbit

View answer & explanation

Correct answer

Answer: (b)B.

Blind spot

Why this answer is correct

The correct answer is Blind spot.

Key Points

  • The blind spot in the human eye is the area on the retina where the optic nerve exits the eye, also known as the optic disc.
  • This region lacks photoreceptor cells (rods and cones), making it insensitive to light.
  • The blind spot is located slightly nasal to the fovea in the visual field of each eye.
  • Despite the presence of a blind spot, the brain compensates for it by using information from the other eye or by filling in the missing details, making it unnoticeable under normal circumstances.
  • The phenomenon of the blind spot was first discovered by the French scientist Edme Mariotte in the 17th century.

Additional Information

  • Fovea
  • The fovea is a small depression in the retina that contains a high concentration of cones.
  • It is responsible for sharp central vision, enabling activities like reading and driving.
  • Photoreceptor Cells
  • There are two types of photoreceptor cells in the retina: rods and cones.
  • Rods are sensitive to low light and help in night vision, while cones are responsible for color vision and work better in bright light.
  • Optic Nerve
  • The optic nerve transmits visual information from the retina to the brain.
  • It is composed of over a million nerve fibers and plays a crucial role in the visual system.
  • Visual Field
  • The visual field is the total area visible to an eye when it is focused on a central point.
  • Each eye has its own blind spot, and their positioning prevents overlap in binocular vision.