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Rajasthan Pharmacist Recruitment Exam 2012 Paper (Previous Year Paper)

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Test (80 questions)

Choose the correct solvents for coating materials

((a))
Glycerin
((b))
Propylene glycol
((c))
Water
((d))
Acetone

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Answer: ((a))

Glycerin

Buffering agent used for parenteral preparation is

((a))
Sodium metabolite
((b))
Sorbitol
((c))
Carbolic acid
((d))
Benzyl alcohol

Show Answer

Answer: ((a))

Sodium metabolite

Choose the correct excipient for enhancing the solubility in tablet manufacturing

((a))
Lactose
((b))
Talc
((c))
Microcrystalline cellulose
((d))
PEG

Show Answer

Answer: ((a))

Lactose

One of the units used for expressing pressure in Torr and is equal to

((a))
Gauss
((b))
Psi
((c))
cm of Hg
((d))
mm of Hg

Show Answer

Answer: ((a))

Gauss

In the process of sugar coating of tablets the colorants are added in one of the following steps

((a))
Syrup coating
((b))
Seal coating
((c))
Sub coating
((d))
Polishing

Show Answer

Answer: ((a))

Syrup coating

The shell of soft gelatin capsule may be elastic or plastic-like, by the addition of

((a))
Povidone
((b))
HPMC
((c))
PEG
((d))
Sorbitol

Show Answer

Answer: ((a))

Povidone

One of the materials listed below is commonly used in film coating of tablets

((a))
Acacia
((b))
HPMC
((c))
Bees wax
((d))
Simple syrup

Show Answer

Answer: ((a))

Acacia

As per G.M.P. permitted limit of solid contents in water for injection is

((a))
100 ppm
((b))
1.0 ppm
((c))
0.1 ppm
((d))
10 ppm

Show Answer

Answer: ((a))

100 ppm

Nujol is

((a))
Hexachlorobutadiene
((b))
Mineral oil
((c))
Perfluorokerosene
((d))
Fluorolube

Show Answer

Answer: ((a))

Hexachlorobutadiene

Which of the following is a microsomal enzyme inducer?

((a))
Indomethacin
((b))
Clofibrate
((c))
Tolbutamide
((d))
Glutethamide

Show Answer

Answer: ((a))

Indomethacin

Fiducial limit is a term used in

((a))
Microbiological assay
((b))
Biological assay
((c))
Chemical assay
((d))
Instrumental methods of assay

Show Answer

Answer: ((a))

Microbiological assay

Phenothiazines are metabolized

((a))
In the hepatic microsomal system by hydroxylation followed by conjugation with glucuronic acid
((b))
In the liver by oxidation
((c))
In the hepatic microsomal system by reduction
((d))
In the hepatic microsomal system by oxidation followed by conjugation with glycine

Show Answer

Answer: ((a))

In the hepatic microsomal system by hydroxylation followed by conjugation with glucuronic acid

Benzodiazepines potentiate

((a))
The binding of protein to nervous tissue
((b))
The binding of GABA to liver
((c))
The binding of GABA to receptors
((d))
The binding of GABA to carbohydrates

Show Answer

Answer: ((a))

The binding of protein to nervous tissue

Benzalkonium chloride is a germicidal surfactant which is rendered inactive in the presence of

((a))
Organic acid
((b))
Cationic surfactants
((c))
Soaps
((d))
Inorganic salts

Show Answer

Answer: ((a))

Organic acid

Which constituent of Guguliipid is responsible for hypolipidemic activity

((a))
Gums
((b))
Gugguisterones E and Z
((c))
Gugguisterol I and II
((d))
All of the above

Show Answer

Answer: ((a))

Gums

Which one of the following is S-glycoside?

((a))
Digoxin
((b))
Sennoside A
((c))
Aloin
((d))
Sinigrin

Show Answer

Answer: ((a))

Digoxin

Which of the following is true about microscopy of Rauwolfia tetraphylla?

((a))
Absence of sclereids
((b))
Non-stratified
((c))
Larger xylem vessels
((d))
All cells are lignified as well as suberized

Show Answer

Answer: ((a))

Absence of sclereids

Ergot gives a blue color with alkali due to the presence of

((a))
Tryptophan residues
((b))
Indole ring
((c))
Ergotoxine
((d))
Lysergic Acid

Show Answer

Answer: ((a))

Tryptophan residues

Ergotine nucleus is derived from

((a))
Ornithine and phenylalanine
((b))
Tryptophan and phenylalanine
((c))
Tryptophan and mevalonate
((d))
5-Hydroxy tryptamine and phenylalanine

Show Answer

Answer: ((a))

Ornithine and phenylalanine

Eserine alkaloids consist of which heterocyclic rings fused together?

((a))
Indole and pyrrole
((b))
Indolidine and pyridine
((c))
Indoline and pyrrolidine
((d))
Indolidine and piperidine

Show Answer

Answer: ((a))

Indole and pyrrole

True statement regarding nitric oxide is

((a))
NO synthesized from arginine
((b))
NO produced spontaneously from NO2
((c))
NO causes vasoconstriction
((d))
NO released from mitochondria

Show Answer

Answer: ((a))

NO synthesized from arginine

Glucose can be synthesized from all of the following except

((a))
Acetoacetate
((b))
Lactic acid
((c))
Glycerol
((d))
Amino acid

Show Answer

Answer: ((a))

Acetoacetate

Gout is a disorder of

((a))
Protein metabolism
((b))
Pyrimidine metabolism
((c))
Oxalate metabolism
((d))
Purine metabolism

Show Answer

Answer: ((a))

Protein metabolism

Most common cause of aortic aneurysm is

((a))
Syphilis
((b))
Marfan’s
((c))
Atherosclerosis
((d))
Congenital

Show Answer

Answer: ((a))

Syphilis

Hemorrhagic infarct may be seen in

((a))
Brain
((b))
Spleen
((c))
Lung
((d))
Heart

Show Answer

Answer: ((a))

Brain

The commonest histological types of lung carcinoma in India are

((a))
Squamous cell carcinoma
((b))
Adenocarcinoma
((c))
Small cell carcinoma
((d))
Large cell carcinoma

Show Answer

Answer: ((a))

Squamous cell carcinoma

The pathological appearance in pseudomembrane colitis is

((a))
Necrosis and gangrene
((b))
Small ulceration with slough
((c))
Serositis covered by membrane
((d))
Excessive ulceration in serosa

Show Answer

Answer: ((a))

Necrosis and gangrene

All of the following arteries supply to the stomach except

((a))
Rt. Gastric artery
((b))
Lt. Gastric artery
((c))
Splenic artery
((d))
Inferior mesenteric artery

Show Answer

Answer: ((a))

Rt. Gastric artery

Which organ has dual blood supply?

((a))
Liver
((b))
Pancreas
((c))
Testis
((d))
Duodenum

Show Answer

Answer: ((a))

Liver

Which of the following spaces will the infection of the index finger spread?

((a))
Mid-palmar space
((b))
Radial bursa
((c))
Thenar space
((d))
Dorsum of hand

Show Answer

Answer: ((a))

Mid-palmar space

The increased incidence of infection in the ischio-rectal fossa is due to

((a))
Absence of deep fascia
((b))
Proximity to anus
((c))
Poor blood supply
((d))
Presence of fibrofatty tissue

Show Answer

Answer: ((a))

Absence of deep fascia

All are true regarding capillaries except

((a))
Have large total cross-sectional area
((b))
Contain larger quantity of blood than veins
((c))
Site of gaseous exchange
((d))
Lined by endothelium

Show Answer

Answer: ((a))

Have large total cross-sectional area

Hyaline membrane contains

((a))
Albumin
((b))
WBCs
((c))
Globulin
((d))
Fibrin

Show Answer

Answer: ((a))

Albumin

Which is the best parameter for analysis of hypoxic hypoxia?

((a))
Arterial PO2
((b))
Arterial PCO2
((c))
Venous PO2
((d))
A-V difference

Show Answer

Answer: ((a))

Arterial PO2

Malaria is caused by

((a))
Plasmodium falciparum
((b))
Plasmodium vivax
((c))
Plasmodium malariae
((d))
All of the above

Show Answer

Answer: ((a))

Plasmodium falciparum

Which of the following are not surface infections?

((a))
Rabies
((b))
Syphilis
((c))
Tetanus
((d))
Trachoma

Show Answer

Answer: ((a))

Rabies

All of the following can cause urinary tract infections except

((a))
Proteus
((b))
Staphylococci
((c))
Faecal streptococci
((d))
E. coli

Show Answer

Answer: ((a))

Proteus

Principal structural component of the cell wall in bacteria is made up of

((a))
Complex polysaccharides
((b))
Simple protein
((c))
Glycoprotein
((d))
Peptidoglycan

Show Answer

Answer: ((a))

Complex polysaccharides

Which of the following are simple RNA viruses except

((a))
Rotavirus
((b))
Influenza virus
((c))
Rabies virus
((d))
Poliovirus

Show Answer

Answer: ((a))

Rotavirus

Adjuvant is a substance which

((a))
Enhances antibody actions
((b))
Enhances adherence of antibody
((c))
Enhances immunogenicity
((d))
Enhances antibody efficacy

Show Answer

Answer: ((a))

Enhances antibody actions

Which of the following is used as preservative in ophthalmic preparation?

((a))
Chlorocresol
((b))
Phenol
((c))
Benzoic acid
((d))
Benzalkonium chloride

Show Answer

Answer: ((a))

Chlorocresol

Which of the following is used as a local anesthetic in the formulation of parenteral products?

((a))
Acetic acid
((b))
Ethyl alcohol
((c))
Benzyl alcohol
((d))
Sorbitol

Show Answer

Answer: ((a))

Acetic acid

Commonly used antioxidant for the oil system is

((a))
Thioglycol
((b))
Ascorbic acid
((c))
Sodium metabisulphite
((d))
Butylated hydroxytoluene

Show Answer

Answer: ((a))

Thioglycol

Half-life equation for first-order reaction is

((a))
$[ T_{1/2} = \frac{a}{2k} ]$
((b))
$[ T_{1/2} = \frac{0.693}{k} ]$
((c))
$[ T_{1/2} = \frac{1}{2a^2k} ]$
((d))
$[ T_{1/2} = \frac{1}{ak} ]$

Show Answer

Answer: ((a))

$[ T_{1/2} = \frac{a}{2k} ]$

Isotonic solution is

((a))
0.1 % NaCl
((b))
0.5 % NaCl
((c))
1.6 % NaCl
((d))
0.9 % NaCl

Show Answer

Answer: ((a))

0.1 % NaCl

In cosmetic preparation, antioxidants used in an aqueous system

((a))
Sodium formaldehyde
((b))
Phenol
((c))
Alpha tocopherol
((d))
Methyl paraben

Show Answer

Answer: ((a))

Sodium formaldehyde

A typical auxin of plants is

((a))
2, 4-D
((b))
NAA
((c))
Indole-3-acetic acid
((d))
Gibberellic acid

Show Answer

Answer: ((a))

2, 4-D

Anthracene has carcinogenic activity

((a))
In general
((b))
If heated in air
((c))
If metabolized
((d))
In ultraviolet light

Show Answer

Answer: ((a))

In general

Best method to estimate blood cholesterol level

((a))
Colorimetric method
((b))
Schales’ method
((c))
Fehling’s method
((d))
Bricker and Butler method

Show Answer

Answer: ((a))

Colorimetric method

Amino acid which is a precursor of serotonin

((a))
Tyrosine
((b))
Tryptophan
((c))
Lysine
((d))
Methionine

Show Answer

Answer: ((a))

Tyrosine

In non-titration of amine halides, the halide ion is removed by the addition of

((a))
Ethyl acetate
((b))
Sodium acetate
((c))
Cellulose acetate
((d))
Mercuric acetate

Show Answer

Answer: ((a))

Ethyl acetate

Milk of magnesia is a preparation containing between 7 and 8.5% of

((a))
Magnesium hydroxide
((b))
Magnesium gluconate
((c))
Magnesium perchlorate
((d))
Magnesium oxide

Show Answer

Answer: ((a))

Magnesium hydroxide

Light-liquid paraffin IP and Liquid Paraffin IP are differentiated by their

((a))
Flash point
((b))
Appearance
((c))
Pour point
((d))
Odour

Show Answer

Answer: ((a))

Flash point

Chronic administration of glucocorticoids results in all of the following adverse effects except

((a))
Hypertension
((b))
Hyperkalaemia
((c))
Proximal myopathy
((d))
Ocular hypertension

Show Answer

Answer: ((a))

Hypertension

Adverse effects of cyclosporin include all of the following except

((a))
Tremor
((b))
Hirsutism
((c))
Nephrotoxicity
((d))
Hypokalaemia

Show Answer

Answer: ((a))

Tremor

Which of the following is a true statement about Corticosteroids

((a))
Inhibits lipocortin production
((b))
Inhibits leukotriene C4 and D4 synthesis
((c))
Inhibits platelet thromboxane A2 synthesis
((d))
Inhibits neutrophil production

Show Answer

Answer: ((a))

Inhibits lipocortin production

Which of the following is true about latanoprost

((a))
Increases trabecular meshwork outflow
((b))
Increases uveoscleral outflow
((c))
Causes papillary dilatation
((d))
Causes iris hyperpigmentation by stimulating the multiplication of melanocytes

Show Answer

Answer: ((a))

Increases trabecular meshwork outflow

Which of the following is a true statement about cocaine

((a))
Is a direct-acting sympathomimetic drug
((b))
Causes pupil dilation in normal people
((c))
Causes pupil constriction in Horner’s syndrome
((d))
Can be used to differentiate between preganglionic and postganglionic Horner’s syndrome

Show Answer

Answer: ((a))

Is a direct-acting sympathomimetic drug

All of the following are side effects seen in α-adrenoreceptor blockers EXCEPT

((a))
Reduced tear production
((b))
Decreased corneal sensation
((c))
Myopic shift
((d))
Impotence

Show Answer

Answer: ((a))

Reduced tear production

All of the following statements are correct about steroids in eyes EXCEPT

((a))
Removal of corneal epithelium will increase the ocular penetration of corticosteroid
((b))
Acetate preparation tends to come in suspension form
((c))
Phosphate preparation has a better corneal penetration than acetate preparation
((d))
Subconjunctival injection of corticosteroid achieves a better ocular penetration than topical instillation

Show Answer

Answer: ((a))

Removal of corneal epithelium will increase the ocular penetration of corticosteroid

Schedule FF contains the list of the following

((a))
Standard for ophthalmic preparation
((b))
Drugs which can be marked under generic names only
((c))
Drugs which are habit-forming
((d))
Standard for cosmetics

Show Answer

Answer: ((a))

Standard for ophthalmic preparation

Application form 19C is used for the following schedule

((a))
Schedule C & C1
((b))
Schedule C
((c))
Homeopathic drugs
((d))
Schedule X

Show Answer

Answer: ((a))

Schedule C & C1

Schedule P includes

((a))
Central drug laboratory
((b))
Life period of drugs
((c))
Good manufacturing practices
((d))
Disinfectant fluids

Show Answer

Answer: ((a))

Central drug laboratory

Schedule L is concerned with

((a))
Habit-forming drugs
((b))
Homeopathic drugs
((c))
Good Laboratory Practices (GLP)
((d))
List of drugs to be sold on prescription only

Show Answer

Answer: ((a))

Habit-forming drugs

Habit-forming and psychotropic drugs are concerned with

((a))
Schedule FF
((b))
Schedule K
((c))
Schedule X
((d))
Schedule D

Show Answer

Answer: ((a))

Schedule FF

State pharmacy council should have the following number of elected members

((a))
Six
((b))
Five
((c))
Nine
((d))
Seven

Show Answer

Answer: ((a))

Six

Schedule O is related to

((a))
Standard for ophthalmic preparation
((b))
Standard for disinfectant fluids
((c))
For external use only
((d))
Standard for cosmetics

Show Answer

Answer: ((a))

Standard for ophthalmic preparation

A mercantile agent who negotiates the purchase or sale of goods on behalf of other parties

((a))
Commission agents
((b))
Factor
((c))
Auctioneer
((d))
Broker

Show Answer

Answer: ((a))

Commission agents

ABC analysis means

((a))
Average better control
((b))
Annual better control
((c))
Always better control
((d))
Arbitrarily better control

Show Answer

Answer: ((a))

Average better control

A test is used to judge the mental capacity of an applicant

((a))
Personality tests
((b))
Proficiency tests
((c))
Aptitude tests
((d))
Intelligence tests

Show Answer

Answer: ((a))

Personality tests

Mercantile agent is also known as

((a))
Agent middleman
((b))
Functional middleman
((c))
Both Agent middleman and Functional middleman
((d))
None of the above

Show Answer

Answer: ((a))

Agent middleman

A merchant who operates entirely by buying and selling in large lots and doesn’t engage in manufacturing or retailing

((a))
Pure wholesaler
((b))
Manufacturer wholesaler
((c))
Retailer wholesaler
((d))
None of the above

Show Answer

Answer: ((a))

Pure wholesaler

Reorder level is equal to

((a))
Maximum usage × Maximum lead time
((b))
Normal usage × Normal lead time
((c))
Minimum usage × Minimum lead time
((d))
Average usage × Average lead time

Show Answer

Answer: ((a))

Maximum usage × Maximum lead time

Annual usage is equal to

((a))
Annual requirement - per unit cost
((b))
Annual requirement x per unit cost
((c))
Annual requirement/per unit cost
((d))
Annual requirement + per unit cost

Show Answer

Answer: ((a))

Annual requirement - per unit cost

Warfarin behaves as a competitive antagonist of

((a))
Vitamin B
((b))
Vitamin C
((c))
Vitamin K
((d))
Vitamin D

Show Answer

Answer: ((a))

Vitamin B

The risk of digitalis toxicity is increased by concomitant administration of

((a))
Triamterene
((b))
Captopril
((c))
Lidocaine
((d))
Hydrochlorothiazide

Show Answer

Answer: ((a))

Triamterene

The xenobiotic that does not cause nephrotoxicity is

((a))
Streptozotocin
((b))
Cisplatin
((c))
Isoniazid
((d))
Gentamycin

Show Answer

Answer: ((a))

Streptozotocin

Choose the drug that often causes tachycardia when given in regular doses

((a))
Isosorbide dinitrate
((b))
Verapamil
((c))
Propranolol
((d))
Guanethidine

Show Answer

Answer: ((a))

Isosorbide dinitrate

Cyclophosphamide is

((a))
Anti-HIV drug
((b))
Analgesic drug
((c))
Anticancer drug
((d))
Antiepileptic drug

Show Answer

Answer: ((a))

Anti-HIV drug

Hyperuricemia is associated with abnormal metabolism of

((a))
Thiamine
((b))
Riboflavin
((c))
Pyrimidines
((d))
Purines

Show Answer

Answer: ((a))

Thiamine

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