The sweetening agent commonly used in the chewable tablet formula is:
- AOption (a)
Sucrose
- BOption (b)
Cyclamate Sodium
- COption (c)
Saccharin Sodium
- DOption (d)
Mannitol
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Correct answer
Sucrose
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The sweetening agent commonly used in the chewable tablet formula is:
Sucrose
Cyclamate Sodium
Saccharin Sodium
Mannitol
Correct answer
Sucrose
Subcoating is given to the tablets:
To increase bulk
To avoid deterioration due to microbial attack
To prevent the solubility in acidic media
To avoid stickiness
Correct answer
To increase bulk
The pH of a pharmaceutical buffer system can be calculated by:
pH partition theory
Noyes Whitney law
Henderson Hasselbalch equation
Michaelis Menten equation
Correct answer
pH partition theory
The pharmacy council of India is constituted by:
Central government
State government
Parliament
Legislative assembly
Correct answer
Central government
Poorly manufactured tablets may have small pinholes on the surface. This phenomenon is known as:
Picking
Mottling
Leaching
Cracking
Correct answer
Picking
Among the following preparations, which one will be the most irritating to the eye:
Purified water
0.7% NaCl solution
0.9% NaCl solution
1% NaCl solution
Correct answer
Purified water
Bubble point test is done to determine:
The surface tension of the liquid in capillary tubes
The viscosity of the liquid in ampoules
The pH of a 1% solution
The volume of a solution stored in a specific container
Correct answer
The surface tension of the liquid in capillary tubes
As per GMP, the permitted limit of solid contents in water for injections is:
100 ppm
1.0 ppm
0.1 ppm
10.0 ppm
Correct answer
100 ppm
License for wholesale of drugs specified in schedule C and C₁ is issued in form:
20A
20B
21B
22A
Correct answer
20A
In capsules, rotofill is used for filling
Powders
Pellets
Liquids
Corrosive liquids
Correct answer
Powders
Which of the following commonly available large volume dextrose solution for intravenous use is isotonic
2.5% W/V
5.0% W/V
10% W/V
20% W/V
Correct answer
2.5% W/V
Which is the ideal combination for testing the solubility of an enteric coated capsule in alkaline medium?
Sodium bicarbonate + Potassium hydroxide + Pepsin
Sodium bicarbonate + Sodium tauroglycocholate + Papain
Sodium bicarbonate + Pancreatin + Sodium tauroglycocholate
Sodium bicarbonate + Bilirubin
Correct answer
Sodium bicarbonate + Potassium hydroxide + Pepsin
Which one of the following is a pseudoalkaloid?
Caffeine
Ephedrine
Morphine
Codeine
Correct answer
Caffeine
Which vitamin contains steroidal structure?
Vitamin E
Vitamin A
Vitamin D
None of the above
Correct answer
Vitamin E
Morphine is present in
Atropa belladonna
Papaver somniferum
Ricinus communis
Solanum nigrum
Correct answer
Atropa belladonna
Emetine, an alkaloid of Ipecacuanha acts as
Antimalarial
Antidiarrhoeal
Antiseptic
Amoebicide
Correct answer
Antimalarial
Patient with Glucose 6 phosphate dehydrogenase deficiency is treated with Dapsone. He will suffer from
Haemolytic anaemia
Pernicious anaemia
Diarrhoea
None of the above
Correct answer
Haemolytic anaemia
Which one of the following drugs is not a long acting benzodiazepine?
Diazepam
Clonazepam
Flurazepam
Midazolam
Correct answer
Diazepam
Which antibiotic is used for the treatment of both tuberculosis as well as leprosy?
Isoniazid (INH)
Rifampicin
Clofazimine
Ethionamide
Correct answer
Isoniazid (INH)
All the following are stimulant purgatives except
Bisacodyl
Castor oil
Senna
Liquid paraffin
Correct answer
Bisacodyl
Mast cell stabilizer is
Salbutamol
Theophylline
Sodium chromoglycate
Atropine
Correct answer
Salbutamol
Anticholinergic used as bronchodilator is
Pilocarpine
Ipratropium
Prazosin
Salbutamol
Correct answer
Pilocarpine
Mucolytics are
Bromohexine
Carbocysteine
Acetyl cysteine
All of the above
Correct answer
Bromohexine
All except ___ are antibiotics obtained from fungi.
Penicillin
Griseofulvin
Cephalosporin
Bacitracin
Correct answer
Penicillin
Some bacteria develop drug resistance very rapidly except
Staphylococci
Coliforms
Streptococcus pyogenes
Tubercle bacilli
Correct answer
Staphylococci
Clavulanic acid or Sulbactum is used in combination with Amoxycillin against H.influenzae because
Clavulanic acid inhibits beta lactamase produced by H.influenzae
Clavulanic acid is acid resistant antibiotic
Clavulanic acid is very susceptible to H.influenzae
None of the above
Correct answer
Clavulanic acid inhibits beta lactamase produced by H.influenzae
Second line antitubercular drug is
Streptomycin
Capreomycin
Ethambutol
Rifampin
Correct answer
Streptomycin
All first line TB drugs are bactericidal except
INH
Rifampicin
Ethambutol
Pyrazinamide
Correct answer
INH
All the following except ___ contain imidazole ring.
Clotrimazole
Econazole
Miconazole
Ketoconazole
Correct answer
Clotrimazole
In congestive cardiac failure, digitalis glycosides are used because it increases
Heart rate
Force of myocardial contraction
Venous pressure
Cardiac filling pressure
Correct answer
Heart rate
In order to produce characteristic pharmacological action, a drug must always
Reach high blood levels
Absorb from G.I. tract readily
Achieve adequate concentration at the site of action
Excreted unchanged in urine
Correct answer
Reach high blood levels
Heparin prevents blood coagulation by
Inhibiting thrombin catalysed conversion of fibrinogen to fibrin
Precipitate blood calcium thereby prevent coagulation reaction
Inhibiting enzyme reactions
Converting ionised calcium by chelation
Correct answer
Inhibiting thrombin catalysed conversion of fibrinogen to fibrin
Which is an antimetabolite?
Fluorouracil
Nitrogen mustard
Cyclophosphamide
Chlorambucil
Correct answer
Fluorouracil
Selective beta2 bronchodilator used for the treatment of status asthmaticus is
Acetyl choline
Isoetharine
Terbutaline
Dirabutero
Correct answer
Acetyl choline
Belladona alkaloid (atropine) is used prior to administration of a general anaesthetic agent due to
Inhibition of G.I.T. motility
Prevention of miosis
Inhibition of salivation and secretion of respiratory tract
Causing skeletal muscle relaxation
Correct answer
Inhibition of G.I.T. motility
Drug of choice in amoebic dysentery is
Penicillin G
Niridazole
Metronidazole
Tetracycline
Correct answer
Penicillin G
Clinically used Uricosuric agent is
Diazepam
Sulfinpyrazone
Phenylbutazone
Phenytoin
Correct answer
Diazepam
The metal used in the treatment of Rheumatoid arthritis is
Ag
Au
Cu
Sb
Correct answer
Ag
The drug very effective in the treatment of acute gout is
Aspirin
Acetaminophen
Phenylbutazone
Indomethacin
Correct answer
Aspirin
The Anti tubercular drug inhibiting RNA synthesis
Streptomycin
Ethambutol
Chloramphenicol
Rifampicin
Correct answer
Streptomycin
The Anti tubercular drug inhibiting Protein synthesis with potential for ototoxic effect is
Ethambutol
Dapsone
Streptomycin
INH
Correct answer
Ethambutol
Methotrexate is an antagonist of
Cobalamine
Folic acid
Riboflavin
Tocopherol
Correct answer
Cobalamine
All are the side effects of Chloroquine except
Blurring of vision
Haemolytic anaemia
Psychotic episodes
Skin rash
Correct answer
Blurring of vision
Antidote of organophosphorus poisoning is
Nitrous oxide
Atenolol
Atropine
Tubocurarine
Correct answer
Nitrous oxide
Which of the following agents is a cholinesterase reactivator?
Aspirin
Pilocarpine
Scopolamine
Pralidoxime
Correct answer
Aspirin
Drug of choice in the treatment of cardiogenic shock is
Diosgenin
Epinephrine
Dopamine
Ouabain
Correct answer
Diosgenin
The choice of drug to treat Cerebral Malaria is
Meparcine
Amodiaquine
Quinine
Primaquine
Correct answer
Meparcine
All of the following statements concerning Sulfonamides are correct except
Inhibit dihydrofolate reductase
Crystalluria may occur
They are antimetabolites of PABA
They are bacteriostatic
Correct answer
Inhibit dihydrofolate reductase
Optic neuritis is a chief adverse effect of
Sulpha drugs
Pyrazinamide
Rifampicin
Ethambutol
Correct answer
Sulpha drugs
Which of the following is not a Macrolide antibiotic?
Erythromycin
Spiramycin
Oleandomycin
Vancomycin
Correct answer
Erythromycin
A steroidal antibiotic is
Fucidin
Bacitracin
Aminophylline
Clindamycin
Correct answer
Fucidin
The preferred treatment of status epilepticus is intra venous administration of
Ethosuximide
Sodium valproate
Diazepam
Chloramphenicol
Correct answer
Ethosuximide
Bromocriptine is used to treat amenorrhea because
It stimulates the ovary
It stimulates the GnRH release
It suppresses the prolactin release
It stimulates FSH release
Correct answer
It stimulates the ovary
The primary mechanism of action of Local Anaesthetic is the blockade of
Potassium channel
Calcium channel
Sodium channel
All of the above
Correct answer
Potassium channel
Long term use of Glucocorticoids induce
Hypotension
Hepatotoxicity
Osteoporosis
Bradycardia
Correct answer
Hypotension
Clomiphene is used to treat infertility because it stimulates
LH secretion
Follicular development
Ovulation
Uterus activity
Correct answer
LH secretion
Isoxuprine is used to treat
Asthma
Severe hypotension
Nasal congestion
Premature labour
Correct answer
Asthma
The phenomena of invasion and destruction of tissue is known as
Natural immunity
Acquired immunity
Pathogenicity
Parasitism
Correct answer
Natural immunity
Organisms that can grow on organic matter from dead plants or animals are called as
Saprophytes
Parasites
Psychotrophs
Mesophils
Correct answer
Saprophytes
Glycerol may be used as a preservative in a percentage of
15
50
1
0.1
Correct answer
15
The micro-organism that can enter the body only through an injury is
Salmonella typhi
Clostridium tetani
Clostridium botulinum
Streptococcus pyogenes
Correct answer
Salmonella typhi
Tears contain an antibacterial enzyme known as
Zymase
Diastase
Lysozyme
Lipase
Correct answer
Zymase
Protein deficiency disease is known as
Cushing’s disease
Fabry’s disease
Parkinson’s disease
Kwashiorkor and marasmus
Correct answer
Cushing’s disease
Glycogen is present in all body tissue except
Liver
Brain
Kidney
Stomach
Correct answer
Liver
The conversion of carotenoids to vitamin A takes place in
Intestine
Liver
Kidney
Skin
Correct answer
Intestine
The precursor of bile salts, sex hormones and vitamin D is
Diosgenin
Cholesterol
Campesterol
Ergosterol
Correct answer
Diosgenin
International enzyme commission classifies enzymes into
Three classes
Six classes
Four classes
Ten classes
Correct answer
Three classes
Platelets contain an enzyme which has an important role in clotting of blood. This enzyme is known as
Cholinesterase
Transaminase
Decarboxylase
Thrombokinase
Correct answer
Cholinesterase
Cobalt is a constituent of
Folic acid
Vitamin B12
Niacin
Biotin
Correct answer
Folic acid
In the process of transcription, the flow of genetic information is from
DNA to DNA
DNA to Protein
DNA to RNA
RNA to DNA
Correct answer
DNA to DNA
Milk is deficient in which mineral?
Phosphorus
Sodium
Iron
Potassium
Correct answer
Phosphorus
Unopened insulin is stored at
-1 to -5°C
2 to 8°C
15 to 20°C
20 to 30°C
Correct answer
-1 to -5°C
Glargine is
Short acting insulin
Intermediate acting insulin
Peakless insulin
Oral insulin
Correct answer
Short acting insulin
Metformin is
Sulfonyl urea
DPP4 inhibitor
Biguanide
Alpha glucosidase inhibitor
Correct answer
Sulfonyl urea
Enalapril is
Angiotensin receptor blocker
Ca channel blocker
Beta blocker
Angiotensin converting enzyme inhibitor
Correct answer
Angiotensin receptor blocker
In primary vaccination DPT is given as
Three doses at one month intervals
Three doses at three month intervals
Five doses at one month intervals
Single dose
Correct answer
Three doses at one month intervals
The following are NSAIDs except
Ibuprofen
Diclofenac sodium
Ketotifen
Piroxicam
Correct answer
Ibuprofen
Dextromethorphan is used in cough syrups as
Expectorant
Mucolytic
Bronchodilator
Suppressant
Correct answer
Expectorant
The following are Proton pump inhibitors except
Omeprazole
Rabiprazole
Pantoprazole
Albendazole
Correct answer
Omeprazole
The following are true of National Pharmaceutical Pricing Authority (NPPA) except
It is a statutory body
It can fund studies regarding pricing of drugs
It monitors drug shortages and takes appropriate action to rectify it
It collects and maintains data regarding the import and export of drugs
Correct answer
It is a statutory body
80 questions in the full paper